Nioclean Gel(20gm)

Nioclean Gel(20gm)

0 5011

Medicine : Nioclean Gel(20gm)

Name:Nioclean Gel(20gm)
Type:Gel
Manufacturer:Klm Laboratories
Generic Use:Clindamycin , Nicotinamide
Composition:Clindamycin(1%) , Nicotinamide(4%)

Generic ( Clindamycin )


Typical use Of Clindamycin :Acne Vulgaris, Babesiosis, Bacterial Infections, Bacterial Vaginosis, Dental Infections, Endocarditis, Hidradenitis Suppurativa, Intra-abdominal Infections, Malaria, Osteomyelitis, Pelvic Infections, Peritonitis, Pulmonary Infection, Septic Arthritis, Septicaemia.
Mechanism of action of Clindamycin :Systemic/vaginal Clindamycin Inhibits Protein Synthesis Of Bacteria By Binding To The 50S Ribosomal Subunits Of The Bacteria. Specifically, It Binds Primarily To The 23s RNA Subunit. Topical Clindamycin Reduces Free Fatty Acid Concentrations On The Skin And Suppresses The Growth Of Propionibacterium Acnes (Corynebacterium Acnes) , An Anaerobe Found In Sebaceous Glands And Follicles.
Drug Interaction of Clindamycin :Clindamycin Is Known To Interact With Other Drugs Like Bamifylline, Calcium Gluconate, Distigmine (Br), Gentamicin, Lincomycin (HCl), Pancuronium (Br), Physostigmine, Rivastigmine, Rocuronium (Br), Sodium Thiosulphate.
Side effects of Clindamycin :Elevated SGPT & SGOT, Elevated Alkaline Phosphatase Concentration, Esophageal Ulceration, Pseudomembranous Colitis, Cardiac Arrest, Colonic Ulceration, Nausea, Vomiting, Abdominal Pain, Rashes, Vaginitis, Contact Dermatitis.

INTERACTIONS OF CLINDAMYCIN


How Clindamycin will impact on Pregnancy ?

Information Not Available.

How Clindamycin will impact during lactation(breastfeeding) ?

Information Not Available.

Medicine & Alcohol use and effect of Clindamycin

Information Not Available.




Generic ( Nicotinamide )


Typical use Of Nicotinamide :To Treat Inflammatory Skin Disease Like Acne, Anxiety And Alzheimer’s Disease
Mechanism of action of Nicotinamide :Nicotinamide Is A Component Of Two Coenzymes, Which Bring About Tissue Respiration, Lipid, Amino Acid, Protein, And Purine Metabolism. Nicotinamide Lowers Blood Cholesterol And Triglyceride Levels By Inhibiting The Synthesis Of Very Low Density Lipoproteins.
Drug Interaction of Nicotinamide :Nicotinamide Is Known To Interact With Other Drugs Like Carbamazepine, Primidone By Reducing Its Clearance. It Also Interacts With Drugs Like Chloramphenicol, Phenytoin, Methotrexate, Penicillamine, Other Vitamins/nutritional Supplements, Antibiotics Like Ciprofloxacin, Levofloxacin And Tetracyclines. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Nicotinamide :Hepatotoxicity, Cholestasis, Portal Fibrosis, Headache, Fatigue, Urge To Vomit (nausea), Stomach Upset, Dizziness, Dry Hair, Diarrhea, Blurred Vision, Flushing And Rash.

INTERACTIONS OF NICOTINAMIDE


How Nicotinamide will impact on Pregnancy ?

Information Not Available.

How Nicotinamide will impact during lactation(breastfeeding) ?

Information Not Available.

Medicine & Alcohol use and effect of Nicotinamide

Information Not Available.




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