Critinem (500mg)

Critinem (500mg)

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Medicine : Critinem (500mg)

Name:Critinem (500mg)
Type:Injection
Manufacturer:Novartis India Ltd (sandoz)
Generic Use:Imipenem , Cilastatin Sodium
Composition:Imipenem(500mg) , Cilastatin Sodium(500mg)

Generic ( Imipenem )


Typical use Of Imipenem :Abdominal Sepsis, Advanced Prostate Cancer, Bone And Joint Infection, Brain Abscesses, Cellulitis, Diabetic Foot Ulcer, Endocarditis, Gastric Acid Reduction During General Anaesthesia, Gynecological Infections, Lower Respiratory Tract Infections, Obstetric Infections, Peritonitis.
Mechanism of action of Imipenem :Imipenem Acts As An Antimicrobial Through The Inhibition Of Cell Wall Synthesis Of Various Gram-positive And Gram-negative Bacteria. This Inhibition Of Cell Wall Synthesis In Gram-negative Bateria Is Attained By Binding To Pencillin Binding Proteins (PBPs).
Drug Interaction of Imipenem :Imipenem Is Known To Interact With Other Drugs Like Ganciclovir (Na), Probenecid. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.
Side effects of Imipenem :Thrombocytopenia, Seizures, Renal Impairment, Leukopenia, Dizziness, Diarrhea, Allergic Reactions, Glossitis, Hypersalivation.

INTERACTIONS OF IMIPENEM


How Imipenem will impact on Pregnancy ?

Information Not Available.

How Imipenem will impact during lactation(breastfeeding) ?

Information Not Available.

Medicine & Alcohol use and effect of Imipenem

Information Not Available.




Generic ( Cilastatin Sodium )


Typical use Of Cilastatin Sodium :Small Cell Carcinoma.
Mechanism of action of Cilastatin Sodium :Cilastatin Is A Specific And Reversible Renal Dehydropeptidase-I Inhibitor. Since The Antibiotic, Imipenem, Is Hydrolyzed By Dehydropeptidase-I, Which Resides In The Brush Border Of The Renal Tubule, Cilastatin Is Administered With Imipenem To Block The Metabolism And Thus The Inactivation Of Imipenem So That Antibacterial Levels Of Imipenem Can Be Attained In The Urine. The Drug Also Prevents The Metabolism Of Leukotriene D4 To Leukotriene E4 Through The Inhibition Of Leukotriene D4 Dipeptidase.
Drug Interaction of Cilastatin Sodium :None Well Documented.
Side effects of Cilastatin Sodium :Diarrhea, Fever, Rashes, Confusion, Allergic Reactions, Nausea And Vomiting, Hearing Loss.

INTERACTIONS OF CILASTATIN SODIUM


How Cilastatin Sodium will impact on Pregnancy ?

Information Not Available.

How Cilastatin Sodium will impact during lactation(breastfeeding) ?

Information Not Available.

Medicine & Alcohol use and effect of Cilastatin Sodium

Information Not Available.




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